Endocrinology

Prof. Dr. Atilla Buyukgebiz

  • Obesity
  • Insulin resistance
  • Diabetes
  • Hypoglycemia (low sugar)
  • Growth retardation and short stature
  • Anorexia
  • growth hormone deficiency
  • Puberty problems (early puberty, delayed puberty, excessive hair growth, menstrual irregularity, polycystic ovary syndrome)
  • Turner syndrome
  • Thyroid diseases (Goiter, hypothyroidism, hyperthyroidism, Hashimoto's disease, thyroid nodule)
  • Sexual development disorders (small penis, undescended testis, gender ambiguity, hypospadias)
  • Adrenal gland diseases (Congenital adrenal hyperplasia, Addison's disease, Cushing's syndrome)
  • Bone and calcium metabolism diseases (rickets, vitamin D deficiency, osteoporosis)

Education:

1990 - 2003
Dokuz Eylul University Faculty of Medicine
Professor (Child Endocrine and Adolescent Department Head)

1990 - 2000
Hacettepe University Faculty of Medicine
Associate professor

1987 - 1990
London Middlesex Hospital, Stanford University (USA) - Hacettepe Faculty of Medicine, Dokuz Eylul Faculty of Medicine
(Pediatric Endocrinology Minor Specialization)

1987 - 1990
Hacettepe University Faculty of Medicine
Assistant professor

1983
Hacettepe Faculty of Medicine
Pediatrics Specialization



Academic Appointments:

2017
Atasehir Florence Nightingale Hospital
Pediatric Endocrinology

2013 - 2017
KadıköyŞifa Ataşehir Hospital
Pediatric Endocrinology

2007
Florence Nightingale Kadıköy Hospital
Pediatric Endocrine (Growth and Adolescence Department Head)

2007 - 2013
Istanbul Science University
Department of Pediatric Endocrine

2004
Republic of Turkey Ministry of Health
Adolescent Health Scientific Committee Membership

2003 - 2007
Acıbadem Hospital
Pediatric Endocrine (Growth and Adolescence Department Head)

2001 - 2004
Republic of Turkey Ministry of Health
Member of Iodine and Iodized Diseases Scientific Committee

1994 - 2000
Bilkent University
Student Health Center Founding Chief Physician

 

MEDICAL AWARDS

- 1977 Hacettepe Faculty of Medicine was selected as the best intern, and Prof.Dr.Gavin C.Arneil and Royal Hospital for Sick Children,Glasgow,Scotland with İhsan Doğramacı scholarship for one month working award
 - 1981 ECFMG certificate (Educational Commission for Medical Graduates, USA)
 - 1984 Cihad Tahsin Gurson Foundation Honorable Mention
 - WHO (World Health Organization) Disease Control Trainer Certificate
 - Tubitak BAYG scholarship (for education at Middlesex Hospital, London)
 - 1991 Award given by Karşıyaka Rotary Club for Congenital Hypothyroidism screening
 - 1992 Award given by Aydın Rotary Club for Congenital Hypothyroidism screening
 - 1993 XXI Middleeastern and Mediterranean Pediatric Society Meeting (Middle Eastern and Mediterranean Countries Pediatrics meeting) second best poster award
 - 1994 European Pediatric Endocrinology Association (ESPE) short-term study fellowship at Stanford University, USA Faculty of Medicine Pediatric Endocrinology unit (visiting scholarship)
 - 1995 Wyeth Science Research award
 - 1997 Wyeth Science Research award
 - 1999 Selected as Merck pharmaceuticals growth hormone research Turkey representative
 - 2000 Turkish Diabetes Foundation best research award (CTLA-4 polymorphism in terms of risk of developing Type 1 Diabetes Mellitus)
 - 2002 National Association of Pediatric Endocrinology meeting, Kayseri second best poster award

 

MEMBERSHIP

2010 ENDO (Endocrine Society - USA) Membership
2008 - 2009 President of the European Society of Pediatric Endocrinology (ESPE)
2006 - 2008 European Society of Pediatric Endocrinology (ESPE) Board Member
1990 European Society of Pediatric Endocrinology (ESPE) Membership
1995 Pediatric Endocrinology Society
1990 - 2003 Aegean Pediatric Endocrinology and Diabetes Association Founding President and Membership
1987 National Pediatric Association

Abaci A, Bekem O, Unuvar T, Ozer E, Bober E, Arslan N, Ozturk Y, Buyukgebiz A. 

Hepatic glycogenosis: a rare cause of hepatomegaly in Type 1 diabetes mellitus. 

J Diabetes Complications. 2008 Sep-Oct;22(5):325-8. Epub 2008 Apr 16. 

Buyukgebiz A, Laron Z. 

Genetic endocrine diseases. Foreword. Pediatr Endocrinol Rev. 2006 Aug;3 Suppl 3:423. No abstract available. Erratum in: Pediatr Endocrinol Rev. 2007 Sep;5(1):470.

Bober E, Dundar B, Demir K, Abaci A, Cakmakçi H, Buyukgebiz A. 

A non-endocrine cause of testicular enlargement mimicking precocious puberty: testicular microlithiasis. J Pediatr Endocrinol Metab. 2007 Nov;20(11):1237-40. 

Sagi L,Zuckerman-Levin N,Gawlik A,Ghizzoni L,Buyukgebiz A,Rakover Y,Bistritzer T,Hochberg Z. Clinical significance of the parental origin of the X chromosome in Turner syndrome. J Clin Endocrinol Metab 2007 92(3):846-52

Darendeli,ler F,Aycan Z,Cetinkaya E,Vidinlisan S,Bas F,Bideci A, Buyukgebiz A, Yıldız M, Bundak R. Effects of Growth hormone on growth,insulin resistance and related hormones (ghrelin,leptin and adinopectin) in Turner syndrome.Horm Res 2007 68(1):1-7 

Abacı A,Bober E,Unuvar T,Atas A, Buyukgebiz A. Case report of two siblings with familial ovarian dysgenesis. Minerva Pediatr 2007 59(1):57-9 

Buyukgebiz A. Hypothlamic hamartoma,gelastic epilepsy and precocious puberty. J Pediatr Endocrinol Metab 2007 20(3):377 

Hızlı S, Abacı A, Buyukgebiz B, Buyukgebiz A. Nutritional stunting. Pediatr Endocr Rev 2007 4:186-96 2006 

Unal E,Abacı A,Bober E, Buyukgebiz A. Efficacy and safety of oral alendronate treatment in children and adolescents with osteoporosis. J Pediatr Endocrinol Metab 2006 19(4):523-8 

Olmez D,Bober E, Buyukgebiz A,Cimrin D. The frequency of vit D insufficiency in healthy female adolescents. Acta Pediatr 2006 95(10):1266-9 

Abacı A,Ataş A,Bober E,Ates O,Hakgider G, Buyukgebiz A. Complex urogenital malformation associated with female pseudohermaphroditism:caudal dysgenesis syndrome. J Pediatr Endocrino Metab 2006 19(9):1171-4 

Buyukgebiz A. Newborn screening for congenital hypothyroidism. J Pediatr Endocrinol Metab 2006 19(11):1291-8

Abaci A, Buyukgebiz A. Gynecomastia: review. Pediatr Endocrinol Rev. 2007 Sep;5(1):489-99.

Buyukgebiz A. The face of late-onset congenital adrenal hyperplasia. 

J Pediatr Endocrinol Metab. 2007 Jun;20(6):667. 2005 

Dundar NO, Anal O, Dundar B, Ozkan H, Caliskan S, Buyukgebiz A.Longitudinal investigation of the relationship between breast milk leptin levels and growth in breast-fed infants. J Pediatr Endocrinol Metab. 2005 Feb;18(2):181-7 

Bober E, Buyukgebiz A,Verrotti A,Chiarelli F. Hypoglycemia,hypoglycemia unawareness and counterregulation in children and adolescents with type1 DM. J Pediatr Endocrinol Metab 2005 18(9):831-41 

Unal E,Abacı A,Bober E, Buyukgebiz A. Oral alendronate in osteogenesis imperfecta. Indian Pediatr 2005 42(11):1158-60 

Dundar B,Dundar N, Erci T, Bober E, Buyukgebiz A. Leptin levels in boys with pubertal gynecomastia. J Pediatr Endocrinol Metab 2005 18(10):929-34 

Darendeliler F,Berberoglu M,Ocal G,Adıyaman P,Bundak R,Ercan G,Can S, Bideci A,Yuksel B, Buyukgebiz A. Response to Growth hormone with respect to pubertal status on increased dose in idiopathic growth hormone deficiency:an anlysis of Turkish children in the KIGS database. J Pediatr Endocrinol Metab 2005 18(10):949-54 

Bober E, Buyukgebiz A.Hypoglycemia and its effects on the brain in children with type1 DM. Pediatr Endocrinol Rev 2005 2(3):378-82 

Genc S, Genc K, Sercan O, Kizildag S, Gulay Z, Atay T, Dundar B, Sakizli M, Analysis of cytotoxic T lymphocyte antigen-4 (CTLA-4) exon 1 polymorphism in patients with type 1 diabetes mellitus in a Turkish population.

J Pediatr Endocrinol Metab. 2004 May;17(5):731-5. 

Buyukgebiz A. Topical testosterone treatment in idiopathic mikropenis. Pediatr Endocr Rev 2004 1(3):334-5 

Kavukcu S, Sahin B, Turkmen M, Soylu A, Lebe B, Buyukgebiz A Horseshoe kidney with mesangioproliferative glomerulonephritis and goiter. Turk J Pediatr. 2003 Oct-Dec;45(4):350-2. 

Dundar B, Bober E, Buyukgebiz A Successful therapy with L-T4 in a 5 year-old boy with generalized thyroid hormone resistance. J Pediatr Endocrinol Metab. 2003 Sep;16(7):1051-6. 

Buyukgebiz A, Bober E. Premature thelarche caused by plant growth factors. J Pediatr Endocrinol Metab. 2003 Feb;16(2):237. 

Buyukgebiz A. Congenital hypothyroidism clinical aspects and late consequences. Pediatr Endocrinol Rev 2003 1(2):185-90

Dundar B, Ercal D, Bober E, Berk T A. Amelogenesis imperfecta with growth hormone deficiency in a 12 year-old boy. J Pediatr Endocrinol Metab. 2002 May;15(5):659-62. 

Cemeroglu AP, Buyukgebiz A Psychogenic diabetes insipidus in toddlers with compulsive bottle-drinking: not a rare entity. J Pediatr Endocrinol Metab. 2002 Jan;15(1):93-4. 2001 

Ober E, Kovanlikaya A, Buyukgebiz A. Primary antiphospholipid syndrome: an unusual cause of adrenal insufficiency. Horm Res. 2001;56(3-4):140-4. 

BuyukgebizA Cemeroglu AP, Bober E, Mohn A, Chiarelli F. Factors influencing remission phase in children with type 1 diabetes mellitus.J Pediatr Endocrinol Metab. 2001 Nov-Dec;14(9):1585-96. Review. 

Vuissoz JM, Deladoey J, Buyukgebiz A, Cemeroglu P, Gex G, Gallati S, Mullis PE.New autosomal recessive mutation of the TSH-beta subunit gene causing central isolated hypothyroidism.J Clin Endocrinol Metab. 2001 Sep;86(9):4468-71. 

Cemeroglu AP, Bober E, Dundar B, Buyukgebiz A. Autoimmune polyglandular endocrinopathy and anterior hypophysitis in a 14 year-old girl presenting with delayed puberty. J Pediatr Endocrinol Metab. 2001 Jul-Aug;14(7):909-14. 

Cemeroglu AP, Bober E, Buyukgebiz A. Prolonged hypocalcemia in a 2 month-old boy unmasking maternal diagnosis of primary hyperparathyroidism. J Pediatr Endocrinol Metab. 2001 Jun;14(6):785-7. 

Buyukgebiz A, Dundar B, Bober E, Buyukgebiz B. Helicobacter pylori infection in children with constitutional delay of growth and puberty.J Pediatr Endocrinol Metab. 2001 May;14(5):549-51.

Bober E, Dundar B,BuyukgebizA. Partial remission phase and metabolic control in type 1 diabetes mellitus in children and adolescents. J Pediatr Endocrinol Metab. 2001 Apr;14(4):435-41. 

Buyukgebiz A, Saylam G, Dundar B, Bober E, Unal N, Akcoral A.Dilated cardiomyopathy as the first early complication in a 14 year-old girl with diabetes mellitus type 1. J Pediatr Endocrinol Metab. 2000 Sep-Oct;13(8):1143-6. 

Dundar B, Akcoral A, Saylam G, Unal N, Mese T, Hudaoglu S, Buyukgebiz B, Bober E, Buyukgebiz A. Chronic hypoxemia leads to reduced serum IGF-I levels in cyanotic congenital heart disease.J Pediatr Endocrinol Metab. 2000 Apr;13(4):431-6. 

Buyukgebiz A, Bober E. Retesting of patients with isolated growth hormone deficiency (IGHD) using provocative tests and reevaluation of them after termination of therapy. J Pediatr Endocrinol Metab. 2000 Feb;13(2):223-4. 

Ozkan H, Aydin A, Demir N, Erci T, Buyukgebiz A.Associations of IGF-I, IGFBP-1 and IGFBP-3 on intrauterine growth and early catch-up growth. Biol Neonate. 1999 Nov;76(5):274-82. 

Buyukgebiz B, Uguz A, Bober E, Buyukgebiz A . Precocious puberty in a patient with indicanuria. J Pediatr Endocrinol Metab. 1999 Jul-Aug;12(4):561-3. 

Buyukgebiz A, Aydin A, Dundar B, Yorukoglu K.Localized lipoatrophy due to recombinant growth hormone therapy in a child with 6.7 kilobase gene deletion isolated growth hormone deficiency. J Pediatr Endocrinol Metab. 1999 Jan-Feb;12(1):95-7. 

Deladoey J, Fluck C, Buyukgebiz A, Kuhlmann BV, Eble A, Hindmarsh PC, Wu W, Mullis PE."Hot spot" in the PROP1 gene responsible for combined pituitary hormone deficiency. J Clin Endocrinol Metab. 1999 May;84(5):1645-50. 43.Korkmaz KS, Sercan OH, Yazicioglu MV, Sakizli M, Darcan S, Buyukgebiz A.A Turkish family with 6.7 Kb deletion associated with isolated growth hormone deficiency type 1A. Turk J Pediatr. 1997 Jan-Mar;39(1):99-104. 

Kavukcu S, Bober E, Akhunlar H, Fadiloglu M, Buyukgebiz A.Effects of recombinant human growth hormone on urinary enzyme excretion of growth hormone deficient children. J Pediatr Endocrinol Metab. 1997 Nov-Dec;10(6):629-31. 

Anal O, Akkoc N, Sen A, Yesil S, Yuksel F, Buyukgebiz A.MHC class I antigen expression in patients with IDDM and their siblings. J Pediatr Endocrinol Metab. 1997 Jul-Aug;10(4):391-4. 

Sen A, Buyukgebiz A.Albumin excretion rate, serum insulin-like growth factor-I and glomerular filtration rate in type I diabetes mellitus at puberty. J Pediatr Endocrinol Metab. 1997 Mar-Apr;10(2):209-15. 

Buyukgebiz A, Bober E, Buyukgebiz B.Vitamin A and beta carotene levels in constitutional delay of growth and puberty. J Pediatr Endocrinol Metab. 1997 Jan-Feb;10(1):51-4. 

Kavukcu S, Turkmen M, Eroglu Y, Canda T, Yorukoglu K, Igci E, Buyukgebiz A.Renal, gastric and thyroidal amyloidosis due to familial Mediterranean fever. Pediatr Nephrol. 1997 Apr;11(2):210-2. 

Uysal K, Uguz A, Olgun N, Sarialioglu F, Buyukgebiz A. Hyperglycemia and acute parotitis related to L-asparaginase therapy. J Pediatr Endocrinol Metab. 1996 Nov-Dec;9(6):627-9. 

Buyukgebiz A,Ercal D,Bober E.Sotos syndrome with septo-optic dysplasia. J Pediatr Endocrinol Metab. 1996 Jul-Aug;9(4):497-9. 

Sercan OH, Korkmaz KS, Yazicioglu MV, Sakizli M, Buyukgebiz A.Two brothers with a 7.0 kb gene deletion associated with isolated growth hormone deficiency type 1A. J Pediatr Endocrinol Metab. 1996 May-Jun;9(3):423-7. 

Bober E, Ozer E, Akgur F, Buyukgebiz A. Bilateral breast masses and bloody nipple discharge in a two year-old boy. J Pediatr Endocrinol Metab. 1996 May-Jun;9(3):419-21. 

Derebek E, Biberoglu S, Kut O, Yesil S, Saydam S, Yilmaz M, Yenici O, Igci E, Gokce O, Canda S, Buyukgebiz A, Dogan AS, Durak H. Early and delayed thallium-201 scintigraphy in thyroid nodules: the relationship between early thallium-201 uptake and perfusion. Eur J Nucl Med. 1996 May;23(5):504-10. 

Buyukgebiz B, Eroglu Y, Buyukgebiz A.Anthropometric and nutritional evaluation of short statured children from low socio-economic class. J Pediatr Endocrinol Metab. 1996 Mar-Apr;9(2):189-92.

Buyukgebiz B, Eroglu Y, Kovanlikaya I, Sen A, Buyukgebiz A.Maroteaux-Lamy syndrome associated with growth hormone deficiency.J Pediatr Endocrinol Metab. 1995 Oct-Dec;8(4):305-7. 

Buyukgebiz A.Treatment of constitutional delayed puberty with a combination of testosterone esters.Horm Res. 1995;44 Suppl 3:32-4. 

Alkin T, BuyukgebizA, Baykara A.Psychosocial considerations in the management of late-diagnosed male pseudohermaphroditism.Turk J Pediatr.1994 Oct-Dec;36(4):303-8. 

Buyukgebiz A, Oktay S. The role of TRH-stimulated prolactin responses in distinguishing gonadotropin deficiency from constitutional delayed puberty.J Pediatr Endocrinol. 1994 Oct-Dec;7(4):325-30. 

BuyukgebizA, Eroglu Y, Karaman O, Kinik E.Biacromical and biiliac length and chest circumference measurements of male Turkish adolescents according to biological maturation. Acta Paediatr Jpn. 1994 Feb;36(1):84-7. 

BuyukgebizA, Eroglu Y, Karaman O, Kinik E.Height and weight measurements of male Turkish adolescents according to biological maturation. Acta Paediatr Jpn. 1994 Feb;36(1):80-3. 1993 

BuyukgebizA.Treatment of constitutional delayed puberty with a combination of testosterone esters. Turk J Pediatr. 1993 Oct-Dec;35(4):271-5.

BuyukgebizA, Kovanlikaya I.Oxandrolone therapy in skeletal dysplasia. Turk J Pediatr. 1993 Jul-Sep;35(3):189-96. 

Buyukgebiz A, Oren H, Unsal E, Akcoral A, Ozen E, Sakizli M. A case of mixed gonadal dysgenesis with 45 X/46 XY karyotype and aortic coarctation. J Pediatr Endocrinol. 1993 Apr-Jun;6(2):191-6. 

Tamugur E, Oren B,Buyukgebiz>A. A case report: familial hypoalphalipoproteinemia. J Pediatr Endocrinol. 1993 Apr-Jun;6(2):185-90. 

Buyukgebiz A, Ciliv G, Kinik E.Lipids and lipoproteins in the sexual maturation stages of male adolescents.Turk J Pediatr. 1991 Jan-Mar;33(1):19-25. 

Buyukgebiz A, Kinik E. Acute maxillary sinusitis treated with cefaclor. Mikrobiyol Bul. 1990 Oct;24(4):379-82. Turkish. 

Tse WY, Buyukgebiz A, Hindmarsh PC, Stanhope R, Preece MA, Brook CG.Long-term outcome of oxandrolone treatment in boys with constitutional delay of growth and puberty.J Pediatr. 1990 Oct;117(4):588-91. 

Buyukgebiz A, Hindmarsh PC, Brook CG. Treatment of constitutional delay of growth and puberty with oxandrolone compared with growth hormone. Arch Dis Child. 1990 Apr;65(4):448-9. 

BuyukgebizA, Kinik E.Sotos syndrome presenting with epilepsy. Turk J Pediatr. 1990 Jan-Mar;32(1):59-63. Review. 

Buyukgebiz A, Kinik E. Nipple development in female puberty. Turk J Pediatr. 1989 Oct-Dec;31(4):275-9. 

Guvenc H, Yurdakok M, Kinik E,Buyukgebiz A. The incidence of pubertal gynecomastia in boys living in the Ankara region. Turk J Pediatr. 1989 Apr-Jun;31(2):123-6. 

Kinik E, Karaman O, B>uyukgebiz>A. Determination of various parameters of sexual maturity in adolescent boys in Ankara.Turk J Pediatr. 1987 Oct-Dec;29(4):217-26. 

Buyukgebiz A, Kinik E, Berkman E. Childhood and adolescent acute maxillary sinusitis. Mikrobiyol Bul. 1987 Oct;21(4):251-6. Turkish. 

Buyukgebiz B, Buyukgebiz A, Kanra G, Kinik E. Acute maxillary sinusitis treated with spiramycin. Mikrobiyol Bul. 1987 Jul;21(3):181-4. Turkish. 

Buyukgebiz A, Kinik E.Acne vulgaris in adolescence. Turk J Pediatr. 1987 Apr-Jun;29(2):95-100.

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