- Breast cancer
- Gynecological cancers (ovary, uterus, cervix)
- Lung cancer
- Immunotherapies
- Colorectal cancers
- Gastric cancer
- Urogenital cancers
- Bone and soft tissue cancers
- Skin cancers
- Molecular oncology
- Head and neck cancers
Higher Education IU Cerrahpaşa Faculty of Medicine Department of Medicine in English (1995-2002) Internship Abroad
1.At the Ottawa Heart Institute, University of Ottawa, Canada
2.6th grade elective cardiology internship (01-31 July 2001)
Specialization in Internal Medicine Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine (2002-2007 December)
Internal Medicine specialist title March 2008
Medical Oncology specialization May 2008 Minor Turkey 5th degree
Istanbul University, Istanbul Faculty of Medicine, Department of Internal Medicine, Department of Medical Oncology (July 2008-January 2012)
Medical Oncology Specialist Title February 2012 Associate Professor title (medical oncology): May 21, 2013
Good Clinical Practices
September 20, 2010 Milan, Italy
Fondazione IRCCS Istitute Nazionale Dei Tumori (Master Course Director was Pinuccia Valagussa)
- Hitit University Çorum Training and Research Hospital, Medical Oncology (Compulsory Service) (May 2012-January 2014)
- Istanbul University Oncology Institute, Department of Medical Oncology, Istanbul (February 2014- August 2016)
- Private Zeytinburnu Avrasya Hospital
Foreign Languages
- Advanced English
- German
Membership
- Turkish Medical Oncology Association
- American Society of Clinical Oncology
- International Association for The Study of Lung Cancer
- Turkish Internal Medicine Specialization Association
A1. Sen F, Yildiz I, Odabas H, Tambas M, Kilic L, Karadeniz A, Altun M, Ekenel M, Serilmez M, Duranyildiz D, Bavbek S, Basaran M. Diagnostic value of serum M30 and M65 in patients with nasopharyngeal carcinoma. Tumour Biol. 2015 Feb;36(2):1039-44. doi: 10.1007/s13277-014-2708-0.
A2. Sen F, Tambas M, Ciftci R, Toz B, Kilic L, Bozbey HU, Karanlik H, Kurul S, Vatansever S, Oral EN, Saglam EK, Kizir A, Saip P, Aydiner A. Factors affecting progression-free survival in non-HIV-related Kaposi sarcoma. J Dermatolog Treat. 2016;27(3):275-7. doi: 10.3109/09546634.2015.1094177.
A3. Sen F, Tambas M, Ozkaya K, Guveli ME, Ciftci R, Ozkan B, Oral EN, Saglam EK, Saip P, Toker A, Demir A, Firat P, Aydiner A, Eralp Y. Concomitant etoposide and cisplatin provided improved survival compared with docetaxel and cisplatin in patients with locally advanced non-small cell lung cancer treated with chemoradiotherapy. Medicine (Baltimore). 2016 Jul;95(30):e4280. doi: 10.1097/MD.0000000000004280.
A4. Sen F, Yildiz I, Basaran M, Ekenel M, Oz F, Kilic L, Toz B, Gurdal A, Camlica H, Bavbek S, Oflaz H. Impaired coronary flow reserve in metastatic cancer patients treated with sunitinib. J BUON. 2013 Jul-Sep;18(3):775-81.
A5. Sen F, Saglam EK, Toker A, Dilege S, Kizir A, Oral EN, Saip P, Sakallioglu B, Topuz E, Aydiner A. Weekly docetaxel and cisplatin with concomitant radiotherapy in addition to surgery and/or consolidation chemotherapy in stage III non-small cell lung cancer. Cancer Chemother Pharmacol. 2011 Dec;68(6):1497-505. doi: 10.1007/s00280- 011-1642-8.
A6. Sen F, Pinarbaşi B, Işsever H, Akyüz F, Mungan Z, Kaymakoğlu S. Postprandial platelet-poor plasma 5- hydroxytryptamine concentrations during diarrhea and constipation periods of alternatingtype irritable bowel syndrome patients. Turk J Gastroenterol. 2011 Jun;22(3):270-8.
A7. Sen F, Karavelioglu Y, Arisoy A. Low-dose tissue plasminogen activator in the treatment of a massive pulmonary thromboembolism in a colon cancer patient treated with bevacizumab: A case report. Oncol Lett. 2014 Dec;8(6):2779-2781.
A8. Sen F, Demirturk M, Abaci N, Golcuk E, Oflaz H, Elitok A, Kutluturk F, Issever H, Unaltuna NE, Ozbey NC. Endothelial nitric oxide synthase intron 4a/b polymorphism and early atherosclerotic changes in hypopituitary GH- deficient adult patients. Eur J Endocrinol. 2008 May;158(5):615-22. doi: 10.1530/EJE-07-0704.
A9. Sen F, Cagatay A, Ozsut H, Calangu S, Eraksoy H, Ozbey N. An unusual association of cutis verticis gyrata with empty sella. Eur J Intern Med. 2008 Oct;19(6):e23-5. doi: 10.1016/j.ejim.2007.06.024. Epub 2008 Feb 13..
A10. Aydiner A, Sen F, Tambas M, Ciftci R, Eralp Y, Saip P, Karanlik H, Fayda M, Kucucuk S, Onder S, Yavuz E, Muslumanoglu M, Igci A. Metaplastic Breast Carcinoma Versus Triple-Negative Breast Cancer: Survival and Response to Treatment. Medicine (Baltimore). 2015 Dec;94(52):e2341. doi: 10.1097/MD.0000000000002341.
A11. Yildiz I, Sen F, Basaran M, Ekenel M, Agaoglu F, Darendeliler E, Tunc HM, Ozcan F, Bavbek S. Response rates and adverse effects of continuous once-daily sunitinib in patients with advanced renal cell carcinoma: a single- center study in Turkey. Jpn J Clin Oncol. 2011 Dec;41(12):1380-7. doi: 10.1093/jjco/hyr151.
A12. Aydiner A, Sen F, Saglam EK, Oral EN, Eralp Y, Tas F, Toker A, Dilege S. Induction chemotherapy with triweekly docetaxel and cisplatin followed by concomitant chemoradiotherapy with or without surgery in stage III non-small-cell lung cancer: a phase II study. Clin Lung Cancer. 2011 Sep;12(5):286-92. doi: 10.1016/j.cllc.2011.03.030.
A13. Yildiz I, Sen F, Ekenel M, Darendeliler E, Bavbek S, Agaoglu F, Ozger H, Eralp L, Bilgic B, Basaran M. Survival and prognostic factors in adult patients with recurrent or refractory ewing sarcoma family tumours: a 13-years retrospective study in Turkey. In Vivo. 2014 May-Jun;28(3):403-9.
A14. Tas F, Sen F, Keskin S, Kilic L, Yildiz I. Prognostic factors in metastatic pancreatic cancer: Older patients are associated with reduced overall survival. Mol Clin Oncol. 2013 Jul;1(4):788-792.
A15. Yildiz I, Sen F, Tuncer S, Kilic L, Basaran M, Bavbek S. Optic disc and choroidal metastasis from sporadic medullary thyroid carcinoma: case report and review of the literature. Onkologie. 2011;34(11):630-3. doi: 10.1159/000334197. Epub 2011 Oct 28. Review.
A16. Tas F, Sen F, Odabas H, Kılıc L, Keskın S, Yıldız I. Performance status of patients is the major prognostic factor at all stages of pancreatic cancer. Int J Clin Oncol. 2013 Oct;18(5):839-46. doi: 10.1007/s10147-012-0474-9.
A17. Saip R, Sen F, Vural B, Ugurel E, Demirkan A, Derin D, Eralp Y, Camlica H, Ustuner Z, Ozbek U. Glutathione S- transferase P1 polymorphisms are associated with time to tumor progression in small cell lung cancer patients. J BUON. 2011 Apr-Jun;16(2):241-6.
A18. Yildiz I, Sen F, Toz B, Kilic L, Agan M, Basaran M. Primary Burkitt’s Lymphoma Presenting as a Rapidly Growing Thyroid Mass. Case Rep Oncol. 2012 May;5(2):388-93. doi: 10.1159/000341260.
A19. Yildiz I, Sen F, Kilic L, Keskin S, Duranyildiz D, Bilgin E, Disci R, Ekenel M, Darendeliler E, Bavbek S, Basaran M. Serum M65 as a biomarker for metastatic renal cell carcinoma. Clin Genitourin Cancer. 2013 Sep;11(3):290-6. doi: 10.1016/j.clgc.2013.01.001.
A20. Oflaz H, Sen F, Bayrakli SK, Elitok A, Cimen AO, Golcuk E, Kasikcioglu E, Tukenmez M, Yazici H, Turkmen A. Reduced coronary flow reserve and early diastolic filling abnormalities in patients with nephrotic syndrome. Ren Fail. 2008;30(9):914-20. doi: 10.1080/08860220802353819.
A21. Oflaz H, Sen F, Elitok A, Cimen AO, Onur I, Kasikcioglu E, Korkmaz S, Demirturk M, Kutluturk F, Pamukcu B, Ozbey N. Coronary flow reserve is impaired in patients with adult growth hormone (GH) deficiency. Clin Endocrinol (Oxf). 2007 Apr;66(4):524-9.
A22. Yildiz I, Sen F, Kilic L, Ciftci R, Basaran M. Intolerance to sunitinib treatment in hemodialysis patients with metastatic renal cell carcinoma. Korean J Urol. 2014 Jan;55(1):74-6. doi: 10.4111/kju.2014.55.1.74.
A23. Tas F, Sen F, Guney N, Keskin S, Camlica H. Triplet chemotherapy combination with cisplatin, gemcitabine and docetaxel in patients with chemotherapy-naive advanced non-small cell lung cancer. Oncol Lett. 2013 May;5(5):1699-1703.
A24. Kilic L, Yildiz I, Sen FK, Erdem MG, Serilmez M, Keskin S, Ciftci R, Karabulut S, Ordu C, Duranyildiz D, Tas F. D- dimer and international normalized ratio (INR) are correlated with tumor markers and disease stage in colorectal cancer patients. Cancer Biomark. 2015;15(4):405-11. doi: 10.3233/CBM-150477.
A25. Yıldız I, Varol U, Şen F, Kılıç L. Cardiac tamponade in a patient treated by sunitinib for metastatic renal cell carcinoma. Anadolu Kardiyol Derg. 2014 Nov;14(7):654-6. doi: 10.5152/akd.2014.5397.
A26. Aydiner A, Toker A, Sen F, Bicakci E, Saglam EK, Erus S, Eralp Y, Tas F, Oral EN, Topuz E, Dilege S. Association of clinical and pathological variables with survival in thymoma. Med Oncol. 2012 Sep;29(3):2221-8. doi: 10.1007/s12032-011-0101-z.
A27. Oflaz H, Kurt R, Sen F, Onur I, Cimen AO, Elitok A, Turkmen K, Pamukcu B, Kasikcioglu E, Bugra Z, Mercanoglu F, Ozbey N. Coronary flow reserve after L-thyroxine therapy in Hashimoto’s thyroiditis patients with subclinical and overt hypothyroidism. Endocrine. 2007 Dec;32(3):264-70. doi: 10.1007/s12020-008-9037-2.
A28. Kalayoglu Beşişik S, Sen F, Midilli K, Yilmaz G, Ozsüt H, Calangu S, Sargin D. [Nosocomial respiratory syncytial virus infections in three cases in a bone marrow transplantation unit]. Mikrobiyol Bul. 2008 Apr;42(2):359-64. Turkish.
A29. Aydiner A, Ciftci R, Sen F. Renin-Angiotensin system blockers may prolong survival of metastatic non-small cell lung cancer patients receiving erlotinib. Medicine (Baltimore). 2015 Jun;94(22):e887. doi: 10.1097/MD.0000000000000887.
A30. Karavelioglu Y, Arisoy A, Sen F. Complete regression of primary epicardial leiomyosarcoma with single agent doxorubicin in an elderly patient. J Chemother. 2013 Dec;25(6):379-80. doi: 10.1179/1973947813Y.0000000080.
A31. Onder S, Taskin OC, Sen F, Topuz S, Kucucuk S, Sozen H, Ilhan R, Tuzlali S, Yavuz E. High expression of SALL4 and fascin, and loss of E-cadherin expression in undifferentiated/dedifferentiated carcinomas of the endometrium: An immunohistochemical and clinicopathologic study. Medicine (Baltimore). 2017 Mar;96(10):e6248. doi: 10.1097/MD.0000000000006248.
A32. Guveli H, Guveli ME, Sen F, Oflaz S, Gurdal N, Tambas M, Kucucuk S, Aydıner A, Ozkan M. Effect of the childhood trauma on the adjustment to cancer in the patients with breast cancer. Breast Cancer. 2017 Jul;24(4):544-551. doi: 10.1007/s12282-016-0737-9.
A33. Faruk Aykan N, Yildiz I, Sen F, Kilic L, Keskin S, Ciftci R, Karabulut S, Sakar B, Disci R. Effect of increased body mass index (BMI) on time to tumour progression (TTP) in unresectable metastatic colorectal cancer (mCRC) patients treated with bevacizumab-based therapy. Med Oncol. 2013;30(3):679. doi: 10.1007/s12032-013-0679-4. A34. Saip P, Eralp Y, Sen F, Karaca H, Ozkan M, Cetin B, Benekli M, Kucukoner M, Isikdogan A, Un O, Basaran G, Onur H. Phase II study of lapatinib in combination with vinorelbine in patients with HER2 positive recurrent or metastatic breast cancer: a multicentric Turkish Oncology Group (TOG) trial. Breast. 2013 Oct;22(5):628-33. doi: 10.1016/j.breast.2013.07.048.
A35. Oflaz S, Yüksel Ş, Şen F, Özdemiroğlu F, Kurt R, Oflaz H, Kaşikcioğlu E. Does Illness Perception Predict Posttraumatic Stress Disorder in Patients with Myocardial Infarction? Noro Psikiyatr Ars. 2014 Jun;51(2):103-109. doi: 10.4274/npa.y6394.
A36. Arısoy A, Memiç K, Karavelioğlu Y, Sen F. Cardiac tamponade as the first clinical sign of gastric adenocarcinoma: a rare condition. Turk Kardiyol Dern Ars. 2014 Jun;42(4):377-9. doi: 10.5543/tkda.2014.24892. A37. Onder S, Fayda M, Karanlık H, Bayram A, Şen F, Cabioglu N, Tuzlalı S, İlhan R, Yavuz E. Loss of ARID1A expression is associated with poor prognosis in invasive micropapillary carcinomas of the breast: A clinicopathologic and immunohistochemical study with long-term survival analysis. Breast J. 2017 May 23. doi: 10.1111/tbj.12823.
A38. Öztürk Sari Ş, Yilmaz İ, Taşkin OÇ, Narli G, Şen F, Çomoğlu Ş, Firat P, Bİlgİç B, Yilmazbayhan D, Özlük Y, Büyükbabanİ N. BRAF, NRAS, KIT, TERT, GNAQ/GNA11 mutation profile analysis of head and neck mucosal melanomas: a study of 42 cases. Pathology. 2017 Jan;49(1):55-61. doi: 10.1016/j.pathol.2016.09.065.
A39. Karanlik H, Ozgur I, Kilic B, Fathalizadeh A, Sanli Y, Onder S, Saip P, Sen F, Gulluoglu BM. Sentinel lymph node biopsy and aberrant lymphatic drainage in recurrent breast cancer: Findings likely to change treatment decisions. J Surg Oncol. 2016 Dec;114(7):796-802. doi: 10.1002/jso.24423.
A40. Kurt A, Karanlık H, Soylu S, Özgür İ, Soydinç HO, Duranyıldız D, Olgaç V, Şen F, Asoğlu O. Effect of intraperitoneal cetuximab administration on colonic anastomosis and early postoperative adhesion formation in a rat model. Ulus Cerrahi Derg. 2015 Sep 1;32(3):157-61. doi: 10.5152/UCD.2016.3250. eCollection 2016.
A41. Kilic L, Ordu C, Yildiz I, Sen F, Keskin S, Ciftci R, Pilanci KN. Current adjuvant treatment modalities for gastric cancer: From history to the future. World J Gastrointest Oncol. 2016 May 15;8(5):439-49. doi: 10.4251/wjgo.v8.i5.439. Review.
A42. Erdemli HK, Kocabas R, Salis O, Sen F, Akyol S, Eskin F, Akyol O, Bedir A, Sahin AF. Is Serum Caveolin-1 a Useful Biomarker for Progression in Patients with Colorectal Cancer? Clin Lab. 2016;62(3):401-8.
A43. Taskin OÇ, Onder S, Topuz S, Sozen H, Sen F, Ilhan R, Yavuz E. A Selected Immunohistochemical Panel Aids in Differential Diagnosis and Prognostic Stratification of Subtypes of High-grade Endometrial Carcinoma: A Clinicopathologic and Immunohistochemical Study at a Single Institution. Appl Immunohistochem Mol Morphol. 2016 Apr 16.
A44. Özmen V, Atasoy A, Gökmen E, Özdoğan M, Güler N, Uras C, Ok E, Demircan O, Işıkkdoğan A, Cabioğlu N, Şen F, Saip P. Correlations Between Oncotype DX Recurrence Score and Classic Risk Factors in Early Breast Cancer: Results of A Prospective Multicenter Study in Turkey. J Breast Health (2013). 2016 Jul 1;12(3):107-111. doi: 10.5152/tjbh.2016.2874.
A45. Karanlik H, Odabas H, Yildirim I, Ozgur I, Kilic B, Sen F, Kurul S, Aydiner A. Is there any effect of first-day usage of a totally implantable venous access device on complications? Int J Clin Oncol. 2015 Dec;20(6):1057-62. doi: 10.1007/s10147-015-0830-7.
A46. Ciftci R, Tas F, Yasasever CT, Aksit E, Karabulut S, Sen F, Keskin S, Kilic L, Yildiz I, Bozbey HU, Duranyildiz D, Vatansever S. High serum transforming growth factor beta 1 (TGFB1) level predicts better survival in breast cancer. Tumour Biol. 2014 Jul;35(7):6941-8. doi: 10.1007/s13277-014-1932-y.
A47. Tas F, Karabulut S, Ciftci R, Sen F, Sakar B, Disci R, Duranyildiz D. Serum levels of LDH, CEA, and CA19-9 have prognostic roles on survival in patients with metastatic pancreatic cancer receiving gemcitabine-based chemotherapy. Cancer Chemother Pharmacol. 2014 Jun;73(6):1163-71. doi: 10.1007/s00280-014-2450-8.
A48. Keskin S, Tas F, Ekenel M, Kilic L, Sen F, Yildiz I, Karabulut S, Ciftci R, Vatansever S. Biweekly triplet chemotherapy with gemcitabine, cisplatin and vinorelbine for advanced chemotherapy naïve non-small cell lung cancer. Tumori. 2013 Jul-Aug;99(4):463-8. doi: 10.1700/1361.15095.
A49. Elitok A, Oz F, Cizgici AY, Kilic L, Ciftci R, Sen F, Bugra Z, Mercanoglu F, Oncul A, Oflaz H. Effect of carvedilol on silent anthracycline-induced cardiotoxicity assessed by strain imaging: A prospective randomized controlled study with six-month follow-up. Cardiol J. 2014;21(5):509-15. doi: 10.5603/CJ.a2013.0150. Epub 2013 Oct 21.
A50. Kilic L, Ordu C, Ekenel M, Yildiz I, Keskin S, Sen F, Gural Z, Asoglu O, Kizir A, Aykan F. Comparison of two different adjuvant treatment modalities for pN3 gastric cancer patients after D2 lymph node dissection: can we avoid radiotherapy in a subgroup of patients? Med Oncol. 2013;30(3):660. doi: 10.1007/s12032-013-0660-2.
A51. Tas F, Karabulut S, Serilmez M, Yildiz I, Sen F, Ciftci R, Duranyildiz D. Clinical significance of serum M30 and M65 levels in melanoma. Melanoma Res. 2013 Oct;23(5):390-5. doi: 10.1097/CMR.0b013e328363e4ab.
A52. Yildiz I, Tas F, Kilic L, Sen F, Saip P, Eralp Y, Keskin S, Karabulut S, Ciftci R, Serilmez M, Yasasever V, Aydiner A. A high serum level of M65 is associated with tumour aggressiveness and an unfavourable prognosis for epithelial ovarian cancer. Cancer Chemother Pharmacol. 2013 Aug;72(2):437-44. doi: 10.1007/s00280-013-2212-z.
A53. Tas F, Karabulut S, Bilgin E, Sen F, Yildiz I, Tastekin D, Ciftci R, Duranyildiz D. Clinical significance of serum M30 and M65 levels in metastatic pancreatic adenocarcinoma. Tumour Biol. 2013 Dec;34(6):3529-36. doi: 10.1007/s13277-013-0931-8.
A54. Tas F, Yildiz I, Kilic L, Ciftci R, Keskin S, Sen F. Same Chemotherapy Regimen Leads to Different Myelotoxicity in Different Malignancies: A Comparison of Chemotherapy-Associated Myelotoxicity in Patients With Advanced Ovarian and Non-Small-Cell Lung Cancer. Am J Ther. 2016 May-Jun;23(3):e670-9. doi: 10.1097/MJT.0b013e31828232b8.
A55. Yildiz I, Ozguroglu M, Toptas T, Turna H, Sen F, Yildiz M. Patterns of complementary and alternative medicine use among Turkish cancer patients. J Palliat Med. 2013 Apr;16(4):383-90. doi: 10.1089/jpm.2012.0226. Epub 2013 Jan 10.
A56. Aydiner A, Kilic L, Yildiz I, Keskin S, Sen F, Kucucuk S, Karanlik H, Muslumanoglu M, Igci A. Two different formulations with equivalent effect? Comparison of serum estradiol suppression with monthly goserelin and trimonthly leuprolide in breast cancer patients.Med Oncol. 2013 Mar;30(1):354. doi: 10.1007/s12032-012-0354-1. A57. Tas F, Kilic L, Bilgin E, Keskin S, Sen F, Ciftci R, Yildiz I, Yasasever V. Clinical and prognostic significance of coagulation assays in advanced epithelial ovarian cancer. Int J Gynecol Cancer. 2013 Feb;23(2):276-81. doi: 10.1097/IGC.0b013e31827b8796.
A58. Tas F, Kilic L, Serilmez M, Keskin S, Sen F, Duranyildiz D. Clinical and prognostic significance of coagulation assays in lung cancer. Respir Med. 2013 Mar;107(3):451-7. doi: 10.1016/j.rmed.2012.11.007.
A59. Tas F, Ciftci R, Kilic L, Bilgin E, Keskin S, Sen F, Yildiz I, Yasasever V. Clinical and prognostic significance of coagulation assays in melanoma. Melanoma Res. 2012 Oct;22(5):368-75. doi: 10.1097/CMR.0b013e328357be7c. A60. Tas F, Keskin S, Karadeniz A, Dağoğlu N, Sen F, Kilic L, Yildiz I. Noncutaneous melanoma have distinct features from each other and cutaneous melanoma. Oncology. 2011;81(5-6):353-8. doi: 10.1159/000334863.
A61. Karanlik H, Kurul S, Saip P, Unal ES, Sen F, Disci R, Topuz E.The role of antibiotic prophylaxis in totally implantable venous access device placement: results of a single-center prospective randomized trial. Am J Surg. 2011 Jul;202(1):10-5. doi: 10.1016/j.amjsurg.2010.05.005.
A62. Gelincik A, Demir S, Şen F, Bozbey UH, Olgaç M, Ünal D, Çolakoğlu B, Aktaş EÇ, Deniz G, Büyüköztürk S. Interleukin-10 is increased in successful drug desensitization regardless of the hypersensitivity reaction type. Asia Pac Allergy. 2019 Jan 28;9(1):e9. doi: 10.5415/apallergy.2019.9.e9.