Neurosurgery
Prof. Dr. Mehmet Ersahin
1. **General Neurosurgical Procedures**
- Craniotomy
- Ventriculoperitoneal Shunting
- Endoscopic Third Ventriculostomy (ETV)
2. **Head and Spinal Injuries**
- Decompression Craniectomy
- Spinal Stabilization
- Treatment of Hematomas and Contusions
3. **Oncological Neurosurgery**
- Brain Tumor Removal (Gliomas, Meningiomas, Metastatic Tumors)
- Radiosurgery (Gamma Knife, CyberKnife)
4. **Vascular Neurosurgery**
- Brain Aneurysms
- Arteriovenous Malformations (AVMs)
- Vascular Embolization
5. **Functional Neurosurgery**
- Deep Brain Stimulation (DBS) for Parkinson's Disease, Essential Tremor, Dystonia
- Neuromodulation for Chronic Pain
6. **Spinal Neurosurgery**
- Microdiscectomy
- Laminectomy
- Spinal Fusion (Spondylodesis)
7. **Minimally Invasive Neurosurgery**
- Endoscopic Procedures
- Laser Ablation of Tumors
Stroke Treatment
1. **Acute Treatment of Ischemic Stroke**
- Thrombolysis (Alteplase/Tissue Plasminogen Activator, tPA)
- Endovascular Thrombectomy
- Anticoagulants and Antiplatelet Agents
2. **Surgical Treatment of Hemorrhagic Stroke**
- Craniotomy for Hematoma Removal
- Aneurysm Clipping
- Coagulation of Arteriovenous Malformations (AVMs)
3. **Rehabilitative Treatment Post-Stroke**
- Physical and Rehabilitation Therapy
- Pharmacotherapy for Stroke Recurrence Prevention
Mesenchymal Stem Cell Treatment (MSCs)
1. **Applications of Mesenchymal Stem Cells**
- Treatment of Spinal Cord Injuries
- Post-Stroke Recovery
- Treatment of Neurodegenerative Diseases (e.g., Parkinson's Disease, Multiple Sclerosis)
2. **Procedures and Treatment Methods**
- MSC Injections into Damaged Brain or Spinal Cord Areas
- Intravenous Infusions of MSCs
- Combined Treatment with Rehabilitation Therapy
3. **Innovative Mesenchymal Stem Cell Therapies for Neurodevelopmental Disorders:**
- Autism
- Cerebral Palsy
- Hypoxia-Induced Developmental Challenges
Other Specialized Procedures
1. **Treatment of Hydrocephalus**
- Shunt Placement (Ventriculoperitoneal, Ventriculoatrial)
- Endoscopic Third Ventriculostomy (ETV)
2. **Treatment of Epilepsy**
- Resection of Epileptogenic Foci
- Laser Ablation of Epileptogenic Foci
- Implantation of Vagus Nerve Stimulators (VNS)
3. **Craniofacial Surgery**
- Reconstruction of Facial Nerves and Muscles
- Surgery for Cranial Deformities
Education:
- 1993 Uludağ University Faculty of Medicine
- 2000 Istanbul Haydarpaşa Numune Training and Research Hospital, Department of Brain and Nerve Surgery
Academic Appointments:
**Professor**: Istanbul Medeniyet University/Faculty of Medicine/Department of Surgical Sciences/Division of Brain and Nerve Surgery (Professor since September 19, 2018, Associate Professor since December 21, 2012)
**Associate Professor**: Istanbul Medeniyet University/Faculty of Medicine (Member of the Board of Directors of the Istanbul Medeniyet University Continuing Education Center)
**Department Head**: Istanbul Medeniyet University/Faculty of Medicine
2010-2012
**Chief of Neurosurgery Clinic**: Ministry of Health Samsun Training and Research Hospital, Chief of Neurosurgery Clinic, Ministry of Health Samsun Training and Research Hospital, Chief of Neurosurgery Clinic (Public)
2000-2010
**Neurosurgery Specialist, Chief Assistant**: Ministry of Health Istanbul Haydarpaşa Numune Training and Research Hospital, Neurosurgery Specialist, Chief Assistant, Ministry of Health Istanbul Haydarpaşa Numune Training and Research Hospital, Neurosurgery Specialist, Chief Assistant (Public)
1994-2000
**Ministry of Health Istanbul Haydarpaşa Numune Training and Research Hospital**
Neurosurgery Research Assistant, Ministry of Health Istanbul Haydarpaşa Numune Training and Research Hospital, Neurosurgery Research Assistant (Public)
1993-1994
**Research Assistant**
**Neurosurgery Specialty Research Assistant**: Samsun 19 Mayıs University Faculty of Medicine, Neurosurgery Research Assistant (Public)
1992-2012
**Dr**
Ministry of Health, (Other)
1992-1994**Health Group President, Government Physician**
Hakkari Çukurca Health Center, Hakkari Çukurca Health Center, Health Group President, Government Physician (Public)
1. Özsavcı, D., Erşahin, M., et al. (2011). "The novel function of nesfatin-1 as an anti-inflammatory and antiapoptotic peptide in subarachnoid hemorrhage–induced oxidative brain damage in rats," **Neurosurgery**.
2. Erşahin, M., et al. (2010). "The anti-inflammatory and neuroprotective effects of ghrelin in subarachnoid hemorrhage-induced oxidative brain damage in rats," **Journal of Neurotrauma**.
3. Ersahin, M., et al. (2009). "Melatonin reduces experimental subarachnoid hemorrhage‐induced oxidative brain damage and neurological symptoms," **Journal of Pineal Research**.
4. Toklu, H.Z., et al. (2010). "Resveratrol improves cardiovascular function and reduces oxidative organ damage in the renal, cardiovascular and cerebral tissues of two-kidney, one-clip hypertensive rats," **Journal of Pharmacy and Pharmacology**.
5. Erşahin, M., et al. (2009). "Melatonin improves cardiovascular function and ameliorates renal, cardiac and cerebral damage in rats with renovascular hypertension," **Journal of Pineal Research**.
6. Toklu, H.Z., et al. (2010). "Neuroprotective effects of alpha-lipoic acid in experimental spinal cord injury in rats," **The Journal of Spinal Cord Medicine**.
7. Erşahin, M., et al. (2010). "Alpha lipoic acid alleviates oxidative stress and preserves blood brain permeability in rats with subarachnoid hemorrhage," **Neurochemical Research**.
8. Erşahin, M., et al. (2012). "Montelukast inhibits caspase-3 activity and ameliorates oxidative damage in the spinal cord and urinary bladder of rats with spinal cord injury," **Prostaglandins & Other Lipid Mediators**.
9. Erşahin, M., et al. (2011). "The effects of Nigella sativa against oxidative injury in a rat model of subarachnoid hemorrhage," **Acta Neurochirurgica**.
10. Ersahin, M., et al. (2011). "The safety and diagnostic value of frame-based and CT-guided stereotactic brain biopsy technique," **Turkish Neurosurgery**.
11. Şahin, A., Erşahin, M., et al. (2012). "Cerebral hemodynamics in patients with carotid stenosis during cross-clamping of the internal carotid artery," **Turkish Neurosurgery**.
12. Çelik, S.E., Erşahin, M., et al. (2010). "Evaluation of oxidative stress in children with acute glomerulonephritis," **Turkish Journal of Pediatrics**.
13. Çelik, S.E., Erşahin, M., et al. (2011). "The neuroprotective effect of nesfatin-1 in subarachnoid hemorrhage," **Neurochemistry International**.
14. Erşahin, M., et al. (2012). "The protective effect of montelukast on oxidative stress in testicular ischemia-reperfusion injury," **Journal of Urology**.
15. Erşahin, M., et al. (2012). "Neuroprotective effects of carvacrol in a rat model of traumatic brain injury," **Journal of Surgical Research**.
16. Erşahin, M., et al. (2013). "Protective effects of ghrelin against ischemia/reperfusion injury of the small intestine in rats," **Surgery Today**.
17. Erşahin, M., et al. (2014). "The role of oxidative stress and inflammation in subarachnoid hemorrhage-induced brain injury," **Turkish Journal of Trauma and Emergency Surgery**.
18. Erşahin, M., et al. (2013). "Neuroprotective effects of atorvastatin against spinal cord injury in rats," **Journal of Neurosurgical Sciences**.
19. Erşahin, M., et al. (2014). "The effects of montelukast on apoptosis in a rat model of spinal cord injury," **Neuroscience Letters**.
20. Erşahin, M., et al. (2015). "The protective effects of melatonin and α-lipoic acid against renal ischemia/reperfusion injury in rats," **Renal Failure**.