Pediatric Surgery
Prof. Dr. Mesrur Selcuk Sılay
1. Pediatric Surgeon – Fields of Interest
Neonatal Surgery
• Congenital diaphragmatic hernia
• Esophageal atresia / tracheoesophageal fistula
• Intestinal atresias, malrotation, Hirschsprung’s disease
• Abdominal wall defects (gastroschisis, omphalocele)
Pediatric Oncological Surgery
• Wilms tumor (nephroblastoma)
• Neuroblastoma
• Hepatoblastoma, hepatocellular carcinoma
• Teratomas and germ cell tumors
Thoracic Surgery
• Congenital lung malformations (CCAM, sequestration)
• Mediastinal tumors
• Chest wall anomalies
Abdominal & Gastrointestinal Surgery
• Appendicitis, Meckel’s diverticulum
• Inflammatory bowel disease (IBD), Crohn’s disease, ulcerative colitis
• Gallbladder and biliary tree diseases
• Splenic and hepatic surgery
Trauma Surgery
• Abdominal, thoracic, and solid organ trauma in children
Minimally Invasive Surgery
• Pediatric laparoscopy and thoracoscopy
• Endoscopic surgical interventions
2. Pediatric Urologist – Fields of Interest
Congenital Urological Anomalies
• Posterior urethral valves (PUV)
• Vesicoureteral reflux (VUR)
• Hydronephrosis, ureteropelvic junction obstruction (UPJO)
• Bladder exstrophy, cloacal anomalies
Pediatric Andrology & Genital Surgery
• Hypospadias, epispadias
• Undescended testis (cryptorchidism)
• Varicocele in adolescents
• Disorders of sex development (DSD)
Functional Urology
• Neurogenic bladder (spina bifida, tethered cord)
• Daytime wetting, enuresis
• Bladder dysfunction syndromes
Pediatric Uro-Oncology
• Wilms tumor (often multidisciplinary with pediatric oncology & surgery)
• Rhabdomyosarcoma of bladder/prostate/genitalia
• Testicular tumors
• Endourology & Minimally Invasive Urology
Pediatric ureteroscopy for stones
• Percutaneous nephrolithotomy (mini-PCNL)
• Laparoscopic/robotic pyeloplasty and nephrectomy
Renal Transplantation in Children
• Pre-transplant evaluation
• Surgical aspects of pediatric kidney transplant
• Long-term surgical follow-up of transplant patients
Education:
• 1997 – Graduated from İskenderun İstiklal Makzume Anadolu Lisesi.
• 2003 – Graduated from Ankara University Faculty of Medicine.
• 2004–2009 – Urology residency, İstanbul Şişli Etfal Training and Research Hospital.
• 2006–2007 – Research in Pediatric Urology and Endourology, The Methodist Hospital, Houston, Texas, USA (6 months).
• 2010 – Research project in Pediatric Urology at Manchester University, UK (awarded €33,000 by European Urology Scholarship Programme).
• 2011 – Obtained Fellow of the European Board of Urology (FEBU) certification.
• 2014 – Earned the academic title of Associate Professor in Urology.
• 2014–2015 – Pediatric Urology Fellowship, Texas Children’s Hospital, Houston, USA (with Prof. Chester Koh, Prof. Patricio Gargollo, Prof. Edmond Gonzalez).
• 2015 – Obtained European Pediatric Urology Fellowship (FEAPU) certification.
Academic Appointments:
• 2003 – Research in Urology, Baylor College of Medicine, Houston, Texas, USA (3 months).
• 2009–2010 – Compulsory service at Diyarbakır Bismil State Hospital.
• 2011–2014 – Assistant Professor, Bezmialem Vakıf University, Faculty of Medicine – performed over 1000 pediatric urology surgeries.
• 2015–2018 – Head of Pediatric Urology Division, İstanbul Medeniyet University Göztepe Training & Research Hospital.
• 2017–2018 – Conducted nearly 100 pediatric robotic surgeries at Mehmet Akif Training & Research Hospital.
• 2018–Present – Consultant Pediatric Urologist, Memorial Hospitals Group.
Leadership & International Roles
• 2010–2012 – President, European Society of Residents in Urology (ESRU).
• 2010–2011 – Editor, European Urology Today journal.
• 2012–Present – Chair, European Association of Urology (EAU) – Young Academic Urologists Pediatric Urology Working Group.
• 2013–Present – Member, European Association of Urology – Pediatric Urology Guidelines Committee (EAU–ESPU).
• 2013–Present – Board Member, EAU Young Urology Office.
• 2014–Present – Board Member, European Society of Genitourinary Reconstructive Surgeons (ESGURS).
• 2015–2017 – Board Member, Turkish Urology Association.
• 2015 – Elected President of the EAU Young Academic Urologists (EAU-YAU), first Turkish urologist to hold this title.
Awards & Recognitions
• Multiple “Best Scientific Presentation” awards (2 in Europe, 4 in Turkey).
• 2016 – Awarded “Academic of the Year” by the Turkish Urology Association
Job
A1. B.Onal, HS.Dogan, N.Satar, CY.Bilen, A.Güneş, E.Ozden, A.Ozturk, D.Demirci, O.Istanbulluoğlu, S.Gurocak, O.Nazli, O.Tanriverdi, A.Kefi, E.Korgali, MS.Silay, K.Inci, V.Izol, R.Altintas, H.Kilicarslan, S.Sarikaya, V.Yalcin, C.Aygun, F.Gevher, IA.Aridogan, S.Tekgul. Factors affecting complication rates of percutaneous nephrolithotomy in children: results of multi-institutional retrospective analysis by Pediatric Stone Disease Study Group of Turkish Pediatric Urology Society. J Urol (ISI), 2013, DOI: 10.1016/j.juro.2013.09.061.
A2. A.Tepeler, AA.Sancaktutar, M.Taskiran, MS.Silay, MN.Bodakci, T.Akman, O.Tanriverdi, B.Resorlu, OF.Bozkurt, A.Armagan, K.Sarica, “Preoperative evaluation of pediatric kidney stone prior to percutaneous nephrolithotomy: is computed tomography really necessary?” Urolithiasis (ISI), 2013, DOI: 10.1007/s00240-013-0593-4.
A3. MS.Silay, A.Tepeler, G.Atis, AA.Sancaktutar, M.Piskin, C.Gurbuz, N.Penbegul, A.Ozturk, T.Caskurlu, A.Armagan, “Initial report of microperc in the treatment of pediatric nephrolithiasis” J Pediatr Surg (ISI), 1578-1583pp, 2013, DOI: 10.1016/j.jpedsurg.2013.06.015.
A4. MS.Silay, AR.Aslan, E.Erdem, Z.Tandogdu, S.Tekgul. Evaluation of functional lower urinary tract dysfunction in children: are the physicians complying with the current guidelines? ScientificWorldJournal (ISI), 2013, DOI: 10.1155/2013/341606.
A5. NK.Hatipoglu, AA.Sancaktutar, A.Tepeler, MN.Bodakci, N.Penbegul, M.Atar, Y.Bozkurt, H.Soylemez, MS.Silay, OM.Istanbulluoglu, T.Akman, A.Armağan, “Comparison of Shockwave Lithotripsy and Microperc for Treatment of Kidney Stones in Children.” J Endourol (ISI), 1141-1146pp., 2013, DOI: 10.1089/end.2013.0066.
A6. MS.Silay, N.Goknar, H.Kilincaslan, A.Tepeler, M.Akcay, T.Akman, O.Uysal, M.Kucukkoc, F.Oktem, A.Armagan, “Who Should We Trust in Screening for Lower Urinary Tract Dysfunction in Children: The Parents or the Child?” Urology (ISI), 437-441pp., 2013, DOI: 10.1016/j.urology.2013.03.021.
A7. N.Dincel, B.Resorlu, A.Unsal, A.Tepeler, MS.Silay, A.Armağan, A.Diri, AA.Sancaktutar, T.Ziypak, S.Mir, “Are small residual stone fragments really insignificant in children?” J Pediatr Surg (ISI), 840-844pp., 2013 DOI: 10.1016/j.jpedsurg.2012.07.061.
A8. MS.Silay, A.Tepeler, AA.Sancaktutar, H.Kilincaslan, B.Altay, MR.Erdem, NK.Hatipoglu, M.Akcay, T.Akman, A.Armagan, “The All-Seeing Needle Instead of the Veress Needle in Pediatric Urologic Laparoscopy” J Endourol (ISI), 2013, DOI: 10.1089/end.2013.0054.
A9. A.Tepeler, MS.Silay, T.Akman, M.Akcay, C.Ersoz, S.Kardas, MR.Erdem, A.Armagan, SY.Onol, “Comparison of flexible and rigid cystoscopy-assisted ureteral catheter insertion before percutaneous nephrolithotomy: a prospective randomized trial.” J Endourol (ISI), 722-726pp., DOI: 10.1089/end.2013.0018.
A10. A.Tepeler, M.Binbay, T.Akman, A.Erbin, C.Kezer, MS.Silay, E.Yuruk, S.Kardas, M.Akçay, A. Armagan, AY.Muslumanoglu, “Parenchymal thickness: does it have an impact on outcomes of percutaneous nephrolithotomy?” Urol Int, 405-410pp., 2013, DOI: 10.1159/000346336.
A11. A.Armagan, MS.Silay, T.Karatag, T.Akman, A.Tepeler, C.Ersoz, M.Akcay, “Circumcision during the phallic period: does it affect the psychosexual functions in adulthood?” Andrologia (ISI), 2013, DOI: 10.1111/and.12071.
A12. MS.Silay, G.Yesil, K.Yildiz, H.Kilincaslan, IT.Ozgen, A.Armagan. ‘’Congenital agenesis of scrotum and labia majora in siblings’’, Urology (ISI), 421-423pp., 2013, DOI: 10.1016/j.urology.2012.10.019.
A13. HM.Stuart, NA.Roberts, B.Burgu, SB.Daly, JE.Urquhart, S.Bhaskar, JE.Dickerson, M.Mermerkaya, MS.Silay, MA.Lewis, MB.Olondriz, B.Gener, C.Beetz, RE.Varga, O.Gülpınar, E.Süer, T.Soygür, ZB.Ozçakar, F.Yalçınkaya, A.Kavaz, B.Bulum, A.Gücük, WW.Yue, F.Erdogan, A.Berry, NA.Hanley, EA.McKenzie, EN.Hilton, AS.Woolf, WG.Newman. ‘’LRIG2 mutations cause urofacial syndrome’’, Am J Hum Genet (ISI), 259-264pp., 2013, DOI: 10.1016/j.ajhg.2012.12.002.
A14. .Tepeler, OF.Bozkurt, B.Resorlu, MS.Silay, E.Ozyuvali, C.Ersoz, M.Akcay, T.Akman, A.Armagan, A.Unsal, “Is the percutaneous nephrolithotomy procedure complicated in patients with anterior caliceal stones?” Urol Int, 389-393pp., 2013, DOI: 10.1159/000345711.
A15. A.Tepeler, MS.Silay, A.Armagan, I.Basibuyuk, T.Akman, M.Akcay, SY.Onol, “Laparoscopic-assisted “microperc” of a stone in a pelvic kidney of a 3-year-old girl.” J Laparoendosc Adv Surg Tech A (ISI), 174-176pp., DOI: 10.1089/lap.2012.0270.
A16. H.Söylemez, AA.Sancaktutar, MS.Silay, N.Penbegül, Y.Bozkurt, M.Atar, B.Altunoluk, MN.Bodakci, NK.Hatipoglu. Knowledge and attitude of European urology residents about ionizing radiation. Urology (ISI), 30-35pp., 2013, DOI: 10.1016/j.urology.2012.07.097.
A17. MS.Silay. Reply By Authors: Snodgraft Technıque In The Treatment Of Prımary Dıstal Hypospadıas Repaır: Pushıng The Envelope. J Urol (ISI), 2012, DOI: 10.1016/j.juro.2012.09.119.
A18. A.Armagan, A.Tepeler, MS.Silay, C.Ersoz, M.Akcay, T.Akman, MR.Erdem, SY.Onol, “Micropercutaneous nephrolithotomy in the treatment of moderate-size renal calculi.” J Endourol (ISI), 177-181pp., 2013, DOI: 10.1089/end.2012.0517.
A19. A.Tepeler, A.Armagan, AA.Sancaktutar, MS.Silay, N.Penbegul, T.Akman, NK.Hatipoglu, C.Ersoz, MR.Erdem, M.Akcay, “The role of microperc in the treatment of symptomatic lower pole renal calculi.” J Endourol (ISI) 13-18pp., 2013, DOI: 10.1089/end.2012.0422.
A20. A.Tepeler, A.Armagan, T.Akman, MS.Sılay, M.Akçay, I.Başıbüyük, MR.Erdem, ŞY.Önol, “Is fluoroscopic imaging mandatory for endoscopic treatment of ureteral stones?” Urology (ISI), 1002-1006pp., 2012, DOI: 10.1016/j.urology.2012.02.082.
A21. MS.Silay, H.Sirin, A.Tepeler, T.Karatag, A.Armagan, K.Horasanli, C.Miroglu, “Snodgraft” technique for the treatment of primary distal hypospadias: pushing the envelope.” J Urol (ISI), 938-942pp.,2012, DOI: 10.1016/j.juro.2012.04.126.
A22. MS.Silay, A.Armagan, H.Kilincaslan, MR.Erdem, M.Akcay. Tubularized incised plate urethroplasty with dorsal inlay graft prevents meatal/neourethral stenosis: a single surgeon’s experience. J Pediatr Surg (ISI), 1480pp., 2012, DOI: 10.1016/j.jpedsurg.2012.02.026.
A23. O.Tanriverdi, MS.Silay, M.Kadihasanoglu, M.Aydin, M.Kendirci, C.Miroglu. Revisiting the predictive factors for intra-operative complications of rigid ureteroscopy: a 15-year experience. Urol J (ISI), 457-464pp., 2012.
A24. A.Tepeler, A.Armağan, Z.Doğan, M.Yılmaz, MS.Sılay. “Re: The efficacy and safety of ureteroscopy for ureteral calculi in pregnancy: our experience in 32 patients.” Urol Res (ISI), 615pp., 2012, DOI: 10.1007/s00240-012-0458-2.
A25. MS.Silay, O.Tanriverdi, C.Miroglu. Re: Preoperative stenting decreases operative time and reoperative rates of ureteroscopy (from: Chu L, Sternberg KM, Averch TD. Preoperative stenting decreases operative time and reoperative rates of ureteroscopy. J Endourol 2011;25:751-754). J Endourol (ISI), 75-76pp., 2012, DOI: 10.1089/end.2011.0203
A26. MS.Silay, O.Tanriverdi, T.Karatag, G.Ozcelik, K.Horasanli, C.Miroglu. Twelve-year experience with Hinman-Allen syndrome at a single center. Urology (ISI), 1397-1401pp., 2011, DOI: 10.1016/j.urology.2011.08.018.
A27. O.Tanriverdi, MS.Silay, M.Kendirci, M.Kadihasanoglu, M.Aydin, K.Horasanli, C.Miroglu. Comparison of ureteroscopic procedures with rigid and semi-rigid ureteroscopes in pediatric population: does the caliber of instrument matter? Pediatr Surg Int (ISI), 2010, 733-738pp., DOI: 10.1007/s00383-010-2630-5.
A28. EC.Serefoglu, MS.Silay. Botulinum toxin-A may be beneficial in the treatment of life-long premature ejaculation. Med Hypotheses (ISI), 2010, 83-84pp., DOI: 10.1016/j.mehy.2009.07.038.
A29. O.Tanriverdi, MS.Silay, C.Miroglu. Re: Computed tomography-determined stone-free rates for ureteroscopy of upper tract stones (from Macejko A, Okotie OT, Zhao LC, Liu J, Perry K, Nadler RB. J Endourol 2009;23:379-382). J Endourol (ISI), 2009, 1919pp., DOI: 10.1089/end.2009.0280.
A30. K.Horasanli, MS.Silay, B.Altay, O.Tanriverdi, K.Sarica, C.Miroglu. Photoselective potassium titanyl phosphate (KTP) laser vaporization versus transurethral resection of the prostate for prostates larger than 70 mL: a short-term prospective randomized trial. Urology (ISI), 2008, 247-251pp., DOI: 10.1016/j.urology.2007.09.017.
A31. K.Horasanli, MS.Silay, C.Miroglu. Re: Al Mosawi AJ: Identification of nonneurogenic neurogenic bladder in infants (Urology 70: 335-356, 2007). Urology (ISI), 2008, 756pp., DOI: 10.1016/j.urology.2007.11.071.
A32. MS.Silay. Comparison of intravesical prostatic protrusion, prostate volume and serum prostatic-specific antigen in the evaluation of bladder outlet obstruction. Int J Urol (ISI), 2007, 672pp., DOI: 10.1111/j.1442-2042.2007.01753.x.
A33. MS.Silay, C.Miroglu. Sunitinib malate and sorafenib may be beneficial at the treatment of advanced bladder cancer due to their anti-angiogenic effects. Med Hypotheses (ISI), 2007, 892-895pp., DOI: 0.1016/j.mehy.2007.01.065.
A34. MS.Silay. Scrotal pouch as a urinary reservoir: a surgical revolution or bizarre hypothesis? Med Hypotheses (ISI), 2007, 233pp., DOI: 10.1016/j.mehy.2006.11.034.
A35. MS.Silay, C.Miroglu. The risk of urolithiasis recurrence may be reduced with anti-nanobacterial therapy. Med Hypotheses (ISI), 2007, 1348-1350pp. DOI: 10.1016/j.mehy.2006.10.027.
A36. MS.Silay. Editorial Comment on Intravesical protrusion of the prostate as a predictive method of bladder outlet obstruction. Int Braz J Urol (ISI), 2008, 34;636.
A37. O.Tanriverdi, MS.Silay, H.Guler, C.Miroglu. Squamous cell carcinoma of the left kidney presenting with splenic hematoma. Int J Nephrol Urol 2009; 1: 65-68.
A.38. Gökçe Mİ, Hajıyev P, Süer E, Kibar Y, Silay MS, Gürocak S, Doğan HS, Irkılata HC, Oktar T, Önal B, Erdem E, Aygün YC, Balcı C, Arslan AR, Kaya C, Soygür T, Sarıkaya S, Tekgül S, Burgu B. Does structured withdrawal of desmopressin improve relapse rates in patients with monosymptomatic enuresis? J Urol 2014; 192:530-4.
A.39. Hatipoglu NK, Tepeler A, Buldu I, Atis G, Bodakci MN, Sancaktutar AA, Silay MS, Daggulli M, Istanbulluoglu MO, Karatag T, Gurbuz C, Armagan A, Caskurlu T. Initial experience of micro-percutaneous nephrolithotomy in the treatment of renal calculi in 140 renal units. Urolithiasis 2014; 42:159-64.
A.40. Tepeler A, Akman T, Silay MS, Akcay M, Ersoz C, Kalkan S, Armagan A, Sarica K. Comparison of intrarenal pelvic pressure during micro-percutaneous nephrolithotomy and conventional percutaneous nephrolithotomy. Urolithiasis 2014; 42: 275-9.
A.41. Kilincaslan H, Silay MS, Erdem MR, Donmez T, Bilici M, Erenberk U. Extraordinary cause of complete colonic obstruction in children: urinary retention. Pediatr Int 2014; 56: 419-22.
A.42. Erdem MR, Tepeler A, Gunes M, Silay MS, Akman T, Akcay M, Armagan A, Onol SY. Laparoscopic decortication of hilar renal cysts using LigaSure. JSLS 2014; 18: 301-7.
A.43. Stuart HM, Roberts NA, Hilton EN, McKenzie EA, Daly SB, Hadfield KD, Rahal JS, Gardiner NJ, Tanley SW, Lewis MA, Sites E, Angle B, Alves C, Lourenço T, Rodrigues M, Calado A, Amado M, Guerreiro N, Serras I, Beetz C, Varga RE, Silay MS, Darlow JM, Dobson MG, Barton DE, Hunziker M, Puri P, Feather SA, Goodship JA, Goodship TH, Lambert HJ, Cordell HJ; the UK VUR Study Group, Saggar A, Kinali M; the 4C Study Group, Lorenz C, Moeller K, Schaefer F, Bayazit AK, Weber S, Newman WG, Woolf AS. Urinary Tract Effects of HPSE2 Mutations. J Am Soc Nephrol 2014; Aug 21. pii: ASN.2013090961.
A.44. Goknar N, Silay MS, Tosuner Z, Oktem F. Rare cause of macroscopic hematuria in a pediatric patient: nephrogenic adenoma of the bladder. Pediatr Int 2014; 56: 611-3.
A.45. Silay MS, Koh CJ. Management of bladder and calyceal diverticulum: Options in the age of minimally invasive surgery. Urol Clin North Am 2015; 42: 77-87.